ser_domain: (1251, 'Client does not support authentication protocol requested by server; consider upgrading MySQL client'): OperationalError
Probably not, but it may be incorrectly set DB URI in config file (or set by -b option).
What version of ser-ctl you are used? (ser_domain -V)
What output is returned when ser-ctl is called with -G and -g switches (eg. ser_domain -Gg ...)?
-- hallik